關於「Aminoacyl-tRNA synthetase active site」標籤，搜尋引擎有相關的訊息討論：

Active site assembly in glutaminyl-tRNA synthetase by ... - NCBI - NIH。

Aminoacyl tRNA-synthetases comprise an ancient class of enzymes that are crucial to maintaining fidelity in the genetic code. They catalyze specific aminoacyl- ...： tw | tw。

Aminoacyl-tRNA synthetases - NCBI。

The aminoacylation reaction. In the first step (A), the amino acid (blue) is activated with ATP (red) in the synthetase active site (not depicted) ...： tw | tw。

Structural plasticity of an aminoacyl-tRNA synthetase active site。

2006年4月25日 · The specificity of the aminoacyl tRNA synthetase is then altered by generating large libraries of active-site mutants and passing them ...： tw | tw。

A rationally engineered misacylating aminoacyl-tRNA synthetase。

2008年5月27日 · GlnRS and GluRS are related members of the subclass 1b tRNA synthetases and possess topologically identical Rossmann fold active site ...。

The structural basis of the genetic code: amino acid recognition by ...。

2020年7月28日 · Aminoacyl-tRNA synthetases are at the heart of this process. ... Hence, a detailed study of the amino acid binding site is the logical next ...。

Active site titration and aminoacyl adenylate binding stoichiometry of ...。

1975年1月14日 · Editing Domain Motions Preorganize the Synthetic Active Site of Prolyl-tRNA Synthetase. ACS Catalysis 2020, 10 (17) , 10229-10242.： tw | tw。

tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting ...。

Because glutaminyl-tRNA synthetase does not possess a spatially separate editing ... This reaction occurs in a second active site that effectively excludes ...。

lessons from aminoacyl‐tRNA synthetases and other amino acid ...。

2019年12月31日 · When do enzymes require editing to boost selectivity? AARSs mechanism of action. Aminoacyl-tRNA synthetases are divided into two classes based ...： tw | tw。

Backbone Brackets and Arginine Tweezers delineate Class I ... - PLOS。

2018年4月16日 · Author summary Aminoacyl tRNA synthetases (aaRS) are primordial ... explain why ATP and tRNA binding sites of both classes seem to be mirror ...。

structural insights into tRNA recognition and aminoacylation。

Aminoacyl-tRNA synthetases are plausible candidates as potential drug ... to the active site and detailed geometry of the acyl donor and tRNA acceptor ...